High-Protein Chicken Broccoli Cheese Casserole

High-Protein Chicken Broccoli Cheese Casserole

Creamy, cheesy chicken and broccoli baked until golden and bubbly — high-protein, low-carb, and ready in 35 minutes

This high-protein chicken broccoli cheese casserole is pure comfort food made low-carb. Tender chicken and broccoli are coated in a rich, creamy cheese sauce and baked until the top is golden and melted. Every serving delivers 32 g of protein and only 4 g net carbs.

Completely sugar-free, family-friendly, and perfect for busy weeknights or meal prep.

Prep10 min
Cook25 min
Servings6
Protein32g
Net Carbs4g
Calories340

Why you’ll love this casserole

  • 32g protein per serving — a complete high-protein meal
  • Only 4g net carbs and fully sugar-free
  • Creamy, cheesy, and deeply comforting
  • Ready in about 35 minutes
  • One baking dish, easy cleanup
  • Excellent for meal prep and leftovers

Health notes

  • High protein: Chicken and cheese create a protein-packed base.
  • Ultra low carb: Broccoli and a cream-cheese sauce keep net carbs very low.
  • Sugar-free: No added sugar of any kind.
  • Vegetable boost: Plenty of broccoli in every serving.

Key element — don’t overcook the broccoli

Slightly undercook the broccoli before assembling so it stays bright green and tender-crisp after baking instead of turning mushy.

Ingredients

Chicken & broccoli

  • 1½–2 lb (680–900g) cooked chicken breast, shredded or cubed (rotisserie works great)
  • 4–5 cups broccoli florets (fresh or frozen)
  • 1 Tbsp olive oil or butter (for cooking broccoli if needed)

Creamy cheese sauce

  • 8 oz (225g) cream cheese, softened
  • ½–¾ cup heavy cream or half-and-half
  • 1½–2 cups shredded cheddar or mozzarella cheese (divided)
  • ½ cup grated Parmesan cheese
  • 2–3 garlic cloves, minced (or ½ tsp garlic powder)
  • ½ tsp onion powder
  • Salt and black pepper to taste
  • Optional: ½ tsp smoked paprika or a pinch of red pepper flakes

To finish

  • Extra shredded cheese for the top
  • Fresh parsley or green onion for garnish

Swaps

  • Turkey or leftover chicken: Any cooked chicken or turkey works.
  • Dairy-free: Use dairy-free cream cheese and shredded cheese alternatives.
  • Extra veggies: Add cauliflower or spinach with the broccoli.
  • Spicy version: Stir in diced jalapeños or a dash of hot sauce.

Instructions

Pro tips

  • Slightly undercook the broccoli so it stays bright and tender after baking.
  • Rotisserie chicken makes this recipe especially fast.
  • For a thicker sauce, use a bit less cream or add an extra ounce of cream cheese.
  • This casserole reheats beautifully and is ideal for meal-prep lunches.
  • Let it rest a few minutes after baking so the sauce sets slightly for cleaner servings.

Nutrition

NutrientPer serving (1/6)
Calories340
Protein32g
Net carbohydrates4g
Total carbohydrates7g
Fiber3g
Total fat20g
Sodium520mg

Estimates based on cooked chicken breast, broccoli, cream cheese, and cheddar. Exact numbers vary with cheese amount and chicken type.

Variations

Extra cheesy

Add an extra ½ cup of shredded cheese to the sauce and on top.

Cauliflower mix

Replace half the broccoli with cauliflower florets for variety.

Bacon boost

Stir in cooked, crumbled bacon for extra flavor and protein.

Spicy version

Add a pinch of cayenne or diced jalapeños to the sauce.

Storage

MethodTimeNotes
RefrigeratorUp to 4 daysCovered; reheat in the oven or microwave
FreezerUp to 2 monthsFreeze before or after baking; thaw overnight in the fridge
Meal prepUp to 4 daysPerfect for grab-and-go high-protein lunches

FAQ

Yes. At only 4g net carbs per serving it fits even strict keto plans.
Yes. Thaw and drain it very well so the casserole doesn’t become watery.
Yes. Assemble up to a day ahead, cover, and refrigerate. Bake when ready, adding a few extra minutes if cold.
Drain the broccoli thoroughly and avoid overcooking it before assembling.
A simple side salad or roasted non-starchy vegetables keep the meal low-carb and balanced.
Yes. Freeze individual portions for up to 2 months. Thaw in the refrigerator and reheat in the oven or microwave.

Test your knowledge

5 quick questions about this chicken broccoli cheese casserole

1. Protein per serving?

2. Net carbs per serving?

3. Why slightly undercook the broccoli?

4. About how long does this take?

5. Best way to serve it?

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